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The overdose of Tapentadol would lead to some risk factors that include depression, addiction to the drug, and seizures. The toxic effects caused by Tapentadol overdose can be reversed just partially by Naloxone but it might increase the risk of seizures in the patient.
There are many death reports that have been recorded which were caused by the usage of Tapentadol overdose and these are still increasing in Northern Ireland. From the report, the overdose has been mostly caused by the drug interaction of Tapentadol with other drugs that include alcohol too. There are many other deaths that have been recorded within the United States and are mostly in Florida. It is better to take a consultation with a licensed physician before procuring Tapentadol.

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Tapentadol SR is an S8 scheduled (controlled) drug indicated for the management of moderate to severe chronic pain unresponsive to non-opioid analgesia. Tapentadol SR may be another option for people with chronic, severe disabling pain for whom non-opioid analgesics provide insufficient pain relief, and for whom a trial of opioids as an alternative is indicated. Addiction, Abuse, and Misuse: Tapentadol oral tablets or extended-release tablets expose users to risks of addiction, abuse, and misuse, which can lead to overdose. Assess patient’s risk before prescribing and monitor regularly for these behaviors and conditions. To ensure that the benefits of opioid analgesics outweigh the risks of addiction, abuse, and misuse, the Food and Drug Administration (FDA) has required a Risk Evaluation and Mitigation Strategy for these products.

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